Mature Epitope Density (MED) 1.0 Server

About MED

MED is a server to predict target proteins for reverse vaccinology according to the number of 9-mer epitopes in the mature protein portion. It makes predictions over amino acid sequences from prokaryotic organisms running the predictors programs SurfG+, TMHMM, and NetMHC.

Sequence Submission

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Usage Information

Restrictions

The limitation is processing time. For 2,000 ORFs, the expected execution time is about 60 minutes.

Confidentiality

The sequences are kept confidential and will be deleted after processing.

Citation

If you use MED in your research, please cite:
Mature Epitope Density – A strategy for target selection based on immunoinformatics and exported prokaryotic proteins

Anderson Santos1,5, Vanessa Pereira1, Eudes Barbosa1,2, Jan Baumbach2,4, Josch Pauling2,4, Richard Rottger2,4, Meritxell Zurita Turk1, Artur Silva3, Anderson Miyoshi1 and Vasco Azevedo1

1 Molecular and Cellular Genetics Laboratory, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brasil.

2 Computational Biology Research Group, Department of Mathematics and Computer Science, University of Southern Denmark, Campusvej, Odense M, Denmark

3 DNA Polymorphism Laboratory, Universidade Federal do Para, Campus do Guama, Belem, Para, Brasil.

4 Computational Systems Biology group, Max Planck Institute for Informatics, Campus E2.1, 66123 Saarbrucken, Germany.

5 Computational Biology Laboratory, Faculty of Computing (FACOM), Universidade Federal de Uberlândia, Uberlândia, Minas Gerais, Brasil.


This software was cited by: Click here to see a list of citing articles and further review information.

Getting Help

Technical and scientific problems: Anderson Santos